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Consult your doctor right away. Its PDE5 inhibiting action releases more of cGMP in the corpus cavernosum of a penis. It’s action at the postsynaptic cleft increases thereby preventing premature ejaculation. It inhibits serotonin reuptake, thereby increasing its amount exponentially in the blood. Malegra DXT is a combination of Sildenafil Citrate and Duloxetine. However, consult your doctor for your dose. Seek immediate medical help if your erection lasts for more than 4 hours. Do not double dose.Duloxetine is a serotonin-norepinephrine reuptake inhibitor. Do not take Malegra DXT with medicines containing nitrates.Take Malegra DXT orally with a light meal at least 60 minutes prior to a sexual activity. Do not consume alcohol or fatty meal to avoid interaction with the medicine. An increased level of cGMP relaxes the smooth muscles of the arteries and improves blood flow into the penis and causes an effective erection. Sildenafil is a selective and reversible inhibitor of phosphodiesterase type 5 with specificity to cGMP.The usual recommended dose is one pill a day.Inform your doctor about other disease conditions you are suffering from and the medications taking.Patients using Malegra DXT may encounter unwanted side effects such as: flushing, headache, dyspepsia, nasal discharge and stuffiness, vision disturbances (blurred vision, photophobia, blue-tinted vision).If it is time for your next dose, then skip the missed dose or else take it as soon as you remember. The effect may last up to many hours.
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